Casting de Oncle Drew
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Kyrie IrvingUncle Drew
Lil Rel HoweryDax Winslow
Shaquille O'NealBig Fella
Chris WebberPreacher- Reggie MillerLights
Nate RobinsonBoots
Lisa LeslieBetty Lou
Erica AshMaya
JB SmooveAngelo
Mike EppsLouis
Tiffany HaddishJess
Nick KrollMookie Bass
Ashton TylerYoung Dax
Aaron GordonCasper Jones- Wesley WitherspoonMario
- Barry RohrssenReferee
Bill WaltonSelf
David RobinsonSelf- Dikembe MutomboSelf
Jamel ChambersAngry Fan
Terence RosemoreCustomer #1
Gage LawsonTeen Playing Basketball (uncredited)
Alannah WilhiteGirl in club
Deadra MooreDesk Nurse- Tinuke AdetunjiAngelo's Girl
