Casting de DMT : The Spirit Molecule
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Joe RoganHimself - Host- Ralph AbrahamHimself - Mathematician
- Joel BakstHimself - Rabbi
- Steven BarkerHimself - Pharmacologist
- Cynthia GeistHerself - DMT Study Nurse
- Susan BlumenthalHerself - DMT Volunteer
- Patricio DominguezHimself - DMT Volunteer
- Neal GoldsmithHimself - Psychologist
Alex GreyHimself - Artist
Roland GriffithsHimself - Behavioral Pharmocologist- Charles GrobHimself - Psychiatrist
- Kathleen HarrisonHerself - Ethnobotanist
Terence McKennaHimself - Writer & Cultural Commentator (archive footage)- Erik DavisHimself - Writer
Graham HancockHimself - Writer- James KentHimself - Writer
Dennis J. McKennaHimself - Ethnopharmacologist
Ralph MetznerHimself - Psychologist- Christian MeuliHimself - DMT Volunteer, Family Physician
Jeremy NarbyHimself - Anthropologist- Andrew NewbergHimself - Radiologist
David NicholsHimself - Medicinal Chemist- Daniel PinchbeckHimself - Writer
Douglas RushkoffHimself - Writer- Spiros AntonopoulosHimself - DMT Volunteer, Yoga Student
- Leanna StandishHerself - Naturopathic Physician
Andrew StoneHimself - DMT Volunteer, Software Developer
Rick StrassmanHimself - Psychiatrist- Robert WeiszHimself - DMT Volunteer, Clinical Psychiatrist
- Ricardo AmaringoHimself
- Alvin JosephHimself
- Jon LevinHimself
- Aja LouxHerself
- José Pineda VargasHimself
- Jordan PhillipsHerself
- Jose PlazaHimself
- Mitch SchultzHimself
- Rob VelezHimself
- Fermin QuintunaHimself
- Ede FrecskaHimself - Psychopharmacologist