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50 CentMarcus
Joy BryantCharlene
Adewale Akinnuoye-AgbajeMajestic
Omar Benson MillerKeryl
Terrence HowardBama
Viola DavisGrandma
Ashley WaltersAntwan
Tory KittlesJustice
Marc John JefferiesYoung Marcus
Sullivan WalkerGrandpa
Bill DukeLevar
Mpho KoahoJunebug- Serena ReederKatrina
Russell HornsbyOdell- Vanessa MaddenMarcus' Relative
Joseph PierreUncle Deuce
Ryan AllenUncle Ray
Brendan JeffersMarcus' Relative- Anastasia HillMarcus' Relative
- Zainab MusaMarcus' Relative
Lawrence BayneSecurity Guard
Boyd BanksPrison Solitary Guard
Lenno BritosCarlos Delgato
Mykelti WilliamsonCharlene's Stepfather (uncredited)
LeonSlim
Rhyon Nicole BrownYoung Charlene
Paulino NunesDetective
Arnold PinnockDetective
Frank PellegrinoDetective Doyle- BubbaEasy / Coke Dealer
- Walter AlzaRaoul
Jer O'LearyValdez- Jorge BerrioCash Counting Machine Operator
Pedro Miguel ArceCash Counting Guard- Mercedez De CastroWoman
Martha ChavesWoman
Pedro SalvínMan- Beatriz PizanoRodrigo's Mom
Arlene DuncanJudge Juvenile Court- Charles Anthony BurksCar Salesman
- Roland RothchildMarcus' Lawyer
Ejyp JohnsonLizard Boot Man (as Curtis 'Ejyp' Johnson)- George RandolphSchool Security Guard
Conrad BergschneiderPrison Guard- Tommy ChangStore Owner
- Vivian LeeStore Owner's Wife
- Ethan James DuffNew Jerseyite
Malik BarnhardtGun Salesman- Michael MillerDangerous
- Don RitchieEmergency Room Doctor
Jean DaiglePrison Corrections Officer- Steve PrempehYoung Antwan
- Cinam ZeeYoung Kid
Shane Francis SmithYoung Kid- H. J. MuellerYoung Kid
- Andrea GrantCharlene's Mother
- Víctor GómezTito
- George GhaliLandlord
Goûchy BoyClub Bouncer
Rogue JohnstonCoin Fiend- Michael ColonneseRaoul's Younger Friend
- Mike SantanaFiend
Benz AntoineRay Wilmore- Mantee MurphyCanary Cook
- Quancetia HamiltonCanary Waitress
Dan DuranJournalist- Destan OwensCharlene's Friend
- Jerome WhitePhotographer
- Bazil WilliamsTeacher
- Juliette NurseTeacher
- Dave NaughtonPrison Tattoo Artist
- Lloyd CokeMajestic Thug
- Roger MooreMajestic Thug
Philip AkinReverend- Nigel HenryMourner
- Dalecia DavisNeighborhood Kid
- Venice GrantHot Girl
- Linda BoahenParty Girl
Amber Shana WilliamsParty Girl- Jessica Rose LengyellParty Girl
- Patricia McPhersonParty Girl
- Tracy JohnsonParty Girl
- Ma’at ZacharyParty Girl (as Keisha 'Ma'at' Zachary)
- Christopher ArmstrongParty Boy
- Randy BrookesND Thug
- Luis FinoStudio Engineer
- Pauline BergerReceptionist
Bruce McFeeSecurity Guard- Wes WilliamsSecurity Guard
Marlon SmithYoung Majestic Thug- Arnold DulmusYoung Majestic Thug
- Jérome KernYoung Majestic Thug
- Jahvan CaesarYoung Majestic Thug
- Jamal CaesarYoung Majestic Thug
- Ray H. McKayYoung Majestic Thug
- Paul McKayYoung Majestic Thug
- Mark McKayYoung Majestic Thug
- Tristan MartinYoung Majestic Thug
- Renee MillerYoung Majestic Hottie
- Keisha DebroTammi (as Keisha Brown)
- Keleisha BrownMonique
Paul De La RosaBaliff- Angelica MenganaReporter
- Kenneth PressmanDiner Paramedic
- Barry MoffattDiner Paramedic
- Joe BoyesDiner Paramedic
- Stefania VammaroGangster's Girlfriend
- DeAdra P. MickelCheck Cashier
- Anarosa PegueroCheck Cashier / Drug Addict
Denia BracheCashier- Keith P. ScottNJ Guy (as Keith Schatt)
- Richardson DesilGun Store Bouncer
Victor of AquitaineMercedes Driver / Drug Buyer (as Victor Fischbarg)- Atif LanierNeighborhood Thug
- Paul D. Coleman Jr.Neighborhood Thug
- Basil GibbsPelham Hall Security Guard
Kevin Dotcom BrownPelham Hall Security Guard (as Kevin Brown)- Rashaad Robert DevoreSubway Man
Balford GordonMarcus Crew Guy- Zachary AugustineMarcus Crew Guy
- Lewis BedfordMarcus Crew Guy
- Anwan EkpoMarcus Crew Guy
- Allan AlexanderMarcus Crew Guy
- Marlon J. HullMarcus Crew Guy
- Jason MooreMarcus Crew Guy
- James OckimeyTeenage Thug
- Vinny CuevasBarber Shop Patron (uncredited)
- Livingston BeaumontPrincipal (uncredited)
Dorly Jean-LouisShanelle Club Babe (uncredited)
Mohamed DioneStreet Thug (uncredited)
Michael YareSound Engineer (uncredited)- Jeshua VargasDriver (uncredited)
- Anthony M. PizzutoProtester (uncredited)
Burton PerezMiguel (uncredited)- Luisa-María LinaresNeighbor (uncredited)
- Shareef McIntoshExtra (uncredited)
- Gloria ParksDominican Hottie (uncredited)