Casting de Cosmos: Une odyssée à travers l'univers
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Neil deGrasse TysonSelf - Host (26 ep.)
Carl SaganSelf (archive footage) (7 ep.)
Sasha SaganRachel Molly Gruber (3 ep.)
Patrick StewartWilliam Herschel (voice) (2 ep.)
Elizardo TorrezYoung Carl Sagan (2 ep.)
Seth MacFarlaneGiordano Bruno (voice) (1 ep.)
John Steven RochaBellaramine (voice) (1 ep.)
Paul TelferAngry Scholar #2 (voice) (1 ep.)
Jonathan Morgan HeitJohn Herschel (voice) (1 ep.)
Cary ElwesEdmond Halley / Robert Hooke (voice) (1 ep.)
Tom KonkleSamuel Pepys (voice) (1 ep.)
Alexander SiddigIsaac Newton (voice) (1 ep.)
Alfred MolinaIbn al-Haytham (voice) (1 ep.)
Stoney EmshwillerGuard (voice) (1 ep.)
Richard GereClair Patterson (voice) (1 ep.)
Piotr MichaelEdmund Muskie (voice) (1 ep.)
Marc WordenHarrison Brown (voice) (1 ep.)
Kirsten DunstCecilia Payne (voice) (1 ep.)
Marlee MatlinAnnie Jump Cannon (voice) (1 ep.)
Peggy Jo JacobsMargaret Harwood (voice) (1 ep.)
Amanda SeyfriedMarie Tharp (voice) (1 ep.)
Christiane AmanpourEnheduanna (voice) (1 ep.)
Michael ChocholJan Oort (1 ep.)
André SogliuzzoChristopher Wren (voice) (1 ep.)- André SogliuzzoWeichelberger (voice) (1 ep.)
Oliver VaquerJoseph von Fraunhofer (voice) (1 ep.)
Christopher EmersonAcolyte (voice) (1 ep.)
Fred TatascioreDemocritus (voice) (1 ep.)
Larry Cedar (1 ep.)- Christopher Emerson (1 ep.)
- Stoney Emshwiller (1 ep.)
Keythe Farley (1 ep.)
Nick Jameson (1 ep.)
Michael McConnohie (1 ep.)
Enn Reitel (1 ep.)- Enn ReitelHenry Norris Russell (voice) (1 ep.)
Masasa Moyo (1 ep.)- Maria Frucci (1 ep.)
- Keythe Farley(voice) (1 ep.)
Martin JarvisHumphry Davy (voice) (1 ep.)
Noah Langford(voice) (1 ep.)
Fay Masterson(voice) (1 ep.)- Piotr MichaelLab Assistant (voice) (1 ep.)
Heiko ObermöllerEinstein's Father (voice) (1 ep.)
Julian OvendenMichael Faraday (voice) (1 ep.)- Jack Rainsford(voice) (1 ep.)
Glenn SteinbaumBruce Heezen (voice) (1 ep.)
William Salyers(voice) (1 ep.)
Paul SorvinoAugustin Mouchot (voice) (1 ep.)
Eliza Schneider(voice) (1 ep.)
Frank BaxterSelf (archive footage) (1 ep.)
John F. KennedySelf (voice) (archive footage) (1 ep.)- Masoumeh HusseiniMonk (voice) (1 ep.)
Harssh A. SinghAshoka (voice) (1 ep.)- Carl SaganSelf (voice) (archive footage) (1 ep.)
Nick Sagan (1 ep.)
Clinnette Minnis (1 ep.)
Shereen BallesFemale Voyager (voice) (1 ep.)
Kapeneta Te'o-TafitiMale Voyager (voice) (1 ep.)- Joseph GrangeJohn Herschel (voice) (1 ep.)
Carol Bach RitaCaroline Herschel (voice) (1 ep.)
Viggo MortensenNikolai Vavilov (voice) (1 ep.)- Seth MacFarlane(voice) (1 ep.)
Ken Lally(voice) (1 ep.)
Phil Crowley(voice) (1 ep.)
Yuri Lowenthal(voice) (1 ep.)
Edita Brychta(voice) (1 ep.)
Christopher Lee Parson(voice) (1 ep.)
Andrew Pifko(voice) (1 ep.)
Brendan Bradley(voice) (1 ep.)
Matthew Jayson Cwern(voice) (1 ep.)
Alan Shearman(voice) (1 ep.)
Natasha Goubskaya(voice) (1 ep.)- Skye Sammoutis(voice) (1 ep.)
Marcelo Tubert(voice) (1 ep.)
Mara Junot(voice) (1 ep.)
Rick Pasqualone(voice) (1 ep.)
Elijah Braik(voice) (1 ep.)
Novi Brown(voice) (1 ep.)
Jamie Hanes (1 ep.)
Will GreenburgJohn Goodricke (1 ep.)- Dex de Groot (1 ep.)
- Joep Fellinger (1 ep.)
Steve OatwayCharles Darwin (1 ep.)
Adam TsekhmanChristiaan Huygens (1 ep.)
Neil ArnoteNeil Armstrong (1 ep.)
Ernie VigilThomas Young (1 ep.)- Seth MacFarlanePresident Harry S. Truman (voice) (1 ep.)
Judd HirschRobert Oppenheimer (voice) (1 ep.)
Olivia d'AboMarie Curie (voice) (1 ep.)- Seth MacFarlaneSherwood Rowland (voice) (1 ep.)
Trang Vo(voice) (1 ep.)- Yurika Okamura(voice) (1 ep.)
- Selyna Chan(voice) (1 ep.)
- Sianna Chan(voice) (1 ep.)
Joseph J. MicucciYoung Father (1 ep.)- Trang VoBirthmark Woman (1 ep.)
Lennard OrtmannAlbert Einstein (1 ep.)
Alex BartramSamuel Sagan (1 ep.)
Brannon BragaWorld's Fair Attendee (1 ep.)
Marcello GuedesYoung Neil deGrasse Tyson (1 ep.)
Leandro GuedesYoung Stephen Joseph Tyson (1 ep.)